GNF
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Supplemental Tables

  • Suppl. Table 1. The list of 156 statistically significant OPI clusters, their ortholog counts in S. cerevisiae and human ortholog, and their P. f. protein counts that form within-cluster networks.

  • Suppl. Table 2. Yeast and human ortholog evidences and protein interaction evidence for assigned and predicted gene ontology memberships of malaria genes.

  • Suppl. Table 3. The complete list of malaria-related PubMed publications.

  • Suppl. Table 4. The complete list of malaria genes cited in each malaria publication.

  • Table column descriptions (XLS file).
  • Additional gene-paper pairs used to constructure GO:PM15591202_Mer/Trp/Spo clusters (CSV file).

Figures (All)

    OPI Clusters & Ortholog Support

    Literature Mining Pipeline

    Probability Density Distributions

    P. k. Validation of Invasion Predictions

    Selected Protein Networks

Additonal Data Files

  • Hierachical clustering results for 156 OPI clusters (Figure 1) (.cdt and .gtr). (To visualize, please download and install the JTreeView program.)

  • Cluster membership for genes in the 156 clusters (CSV.gz file, 0.8MB)

  • Custom P. y. chip definition file (CSV file) and all probes on the array (GZip file).

  • Gene expression matrix for 14 P. yoelii samples (MOID, quantile normalized) (CSV file, 1.0MB).

  • Gene expression matrix for 40 P. falciparum samples (MOID, quantile normalized) (CSV file, 0.6MB).

  • Combined gene expression matrix for all 54 malaria samples (6592 P. f. and P. y. genes) (CSV.gz file, 0.9MB). Sample description file (CSV file).

  • A summary table for all P.f. genes containing information regarding their differential expression, P. yoelii ortholog, human orthologs, and OPI supports (CSV file, 0.5MB).

  • Raw expression data, Affymetrix CEL files (gzip compressed): 14 P. yoelii samples, 2 zygote & ookinete P. falciparum samples, P. falciparum gametocyte stage (Young et al.), other P. falciparum stages (Le Roch et al.).

  • 74 Yeast samples collected at GNF used for ortholog analysis (CSV file, 2.2MB).

  • Human Tissue Atlas data collected at GNF.

  • Hierachical clustering results for remaining gene groups.

      To visualize, please download and install the JTreeView program.)
      736 genes in large OPI clusters (cluster size > 500) (.cdt and .gtr).
      118 genes share similar expression to OPI clusters (.cdt and .gtr).
      1026 genes with distinct expression patterns (.cdt and .gtr).